In silico medicine, particularly through the use of finite element simulations, is revolutionizing patient-specific healthcare, especially in the musculoskeletal system. By creating detailed computational models of individual anatomy, finite element analysis enables precise simulation of biomechanical behavior under various conditions. This approach allows for personalized treatment strategies, offering predictive insights into how specific interventions—such as surgeries, prosthetics or rehabilitation plans—might affect the patient’s musculoskeletal health. Unlike traditional experiments such as in vivo or in vitro, in silico medicine refers to simulations where the experimental environment is recreated within the processor.